VehicleVerdict

2010 Mercedes-Benz E350 problems

Verdict · NHTSA data

One of the years to avoid

The 2010 Mercedes-Benz E350 carries two red flags at once: 229 consumer complaints filed with NHTSA and an open NHTSA defect investigation (subject: Desiccated Air Bag Inflator Rupture). It is one of the E350 years to avoid. Complainants reported 12 injuries in total across these filings.

Airbags leads the complaint categories with 68 reports (30% of the total).

229

NHTSA complaints

4

Recalls

2

Investigations · 1 open

17

Crash-involved

0

Fires reported

12

Injuries

0

Deaths

—

NCAP overall

How does 2010 compare to other E350 years?

E350 NHTSA complaints by model year, 2010 highlighted482 complaints2003: 10 complaints2004: 11 complaints2005: 17 complaints2006: 482 complaints2007: 398 complaints2008: 220 complaints2009: 76 complaints2010: 229 complaints2011: 263 complaints2012: 260 complaints2013: 215 complaints2014: 368 complaints2015: 40 complaints2016: 72 complaints2017: 11 complaints
E350 NHTSA complaints by model year, 2010 highlighted. Red bars are years to avoid.

See all E350 years to avoid →

What are the most common 2010 Mercedes-Benz E350 problems?

ComponentComplaintsShare
Airbags6830%
Electrical System219%
Other209%
Fuel System209%
Suspension177%
Engine167%
Transmission146%
Brakes146%
Body & Structure115%
Steering73%
Tires & Wheels63%
Lighting52%
Speed Control42%
Seats42%
Driver Assistance21%

Does the 2010 Mercedes-Benz E350 have recalls?

4 NHTSA recall campaigns on file. Recall repairs are free at franchised dealers.

22V168000EngineMarch 18, 2022 · 22 units

Defect

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2010 E350, 2014 G550, 2008-2009 C300, 2008 C350, 2009 CLK550, 2007 SL550, SLK280, and 2008 SLK350 vehicles. Various control units may have been updated with incorrect software configuration during a service repair. This can result in various system failures, such as loss of drive power, reduced exterior lighting, or loss of dynamic control functions, including stability and traction control.

Consequence

Various system failures, such as loss of drive power, reduced exterior lighting, or loss of dynamic control functions including stability and traction control, can increase the risk of a crash.

Remedy

Dealers will update the software configuration on the affected control units, free of charge. Owner notification letters were mailed May 3, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040003.

18V043000AirbagsJanuary 10, 2018 · 132,167 units

Defect

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2013 C250, C250 Coupe, C350 Coupe 4Matic, C300 4Matic, C350, C350 Coupe, C63 AMG, C63 Coupe, E350 Cabrio, E350 Coupe, E550 Cabrio, E350 Coupe 4Matic, E550 Coupe, GLK350 4Matic, GLK250 Bluetec 4Matic, GLK350, SLS Coupe, SLS AMG GT Coupe, and SLS Roadster vehicles sold, or ever registered, in the states of Alabama, California, Florida, Georgia, Hawaii, Louisiana, Mississippi, South Carolina, Texas, Puerto Rico, American Samoa, Guam, the Northern Mariana Islands (Saipan), and the U.S. Virgin Islands or "Zone A." Additionally, MBUSA is recalling certain 2010 C300, C300 4Matic, C63 AMG, E350 Coupe, E550 Coupe, GLK350, and GLK350 4Matic vehicles ever registered in the states of Arizona, Arkansas, Delaware, District of Columbia, Illinois, Indiana, Kansas, Kentucky, Maryland, Missouri, Nebraska, Nevada, New Jersey, New Mexico, North Carolina, Ohio, Oklahoma, Pennsylvania, Tennessee, Virginia, and West Virginia or "Zone B." MBUSA is also recalling certain 2009 C300, C300 4Matic, C63 AMG, and C350 vehicles ever registered in the states of AK, CO, CT, ID, IA, ME, MA, MI, MN, MO, NH, NY, ND, OR, RI, SD, UT, VT, WA, WI and WY or "Zone C." In the event of a crash necessitating deployment of the passenger frontal air bag, these passenger air bag inflator may explode due to propellant degradation occurring after long-term exposure to absolute humidity and temperature cycling.

Consequence

An inflator explosion may result in sharp metal fragments striking the driver or other occupants resulting in serious injury or death.

Remedy

MBUSA will notify owners, and dealers will replace the passenger frontal air bag module, free of charge. Mercedes issued an interim notification to owners on February 23, 2018. A second notice will be mailed when remedy parts are available. Owners may contact MBUSA customer service at 1-877-496-3691.

16V363000AirbagsMay 26, 2016 · 258,163 units

Defect

Mercedes-Benz USA, LLC (MBUSA) is recalling certain model year 2008-2011 C300 Sedan, C300 4matic Sedan, C350 Sedan, C63 AMG Sedan vehicles, 2010-2011 GLK350, GLK350 4-Matic and E350 Coupe vehicles, 2011 SLS AMG, E350 Convertible, E550 Coupe and E550 Convertible vehicles originally sold, or ever registered, in Alabama, California, Florida, Georgia, Hawaii, Louisiana, Mississippi, South Carolina, Texas, Puerto Rico, American Samoa, Guam, the Northern Mariana Islands (Saipan), and the U.S. Virgin Islands, or "Zone A." Additionally, unless included in "Zone A" above, MBUSA is recalling certain model year 2008 C300 Sedan, C350 Sedan, C63 AMG Sedan and C300 4-Matic Sedan vehicles originally sold, or ever registered, in Arizona, Arkansas, Delaware, District of Columbia, Illinois, Indiana, Kansas, Kentucky, Maryland, Missouri, Nebraska, Nevada, New Jersey, New Mexico, North Carolina, Ohio, Oklahoma, Pennsylvania, Tennessee, Virginia, and West Virginia, or "Zone B." Vehicles not originally sold or ever registered in either Zones A or B are not subject to this safety recall. These vehicles are equipped with certain air bag inflators assembled as part of the passenger frontal air bag modules, and used as original equipment or replacement equipment. In the event of a crash necessitating deployment of the front air bags, these inflators may rupture due to propellant degradation occurring after long-term exposure to absolute humidity and temperature cycling.

Consequence

An inflator rupture may result in metal fragments striking the vehicle occupants resulting in serious injury or death.

Remedy

MBUSA will notify owners, and dealers will replace the passenger frontal air bag modules, free of charge. Owners were sent an interim notification October 2016. A second notice will be mailed when remedy parts are available. Owners may contact MBUSA customer service at 1-877-496-3691.

16V081000AirbagsFebruary 11, 2016 · 711,159 units

Defect

Mercedes-Benz USA, LLC. (MBUSA) is recalling certain model year 2009-2010 ML320 BlueTec 4Matic, GL320 BlueTec 4Matic and R320 CDI 4Matic, 2011 E350 Cabriolet and E550 Cabriolet, 2009-2011 ML350, ML350 4Matic, ML550 4Matic, ML63 AMG, and C63 AMG, 2010-2011 ML450 4Matic Hybrid, E350 Coupe, E350 4Matic, E550 Coupe, E550 4Matic, and E63 AMG, 2011-2012 GL350 BlueTec 4Matic and R350 BlueTec 4Matic, 2009-2012 GL450 4Matic, GL550 4Matic and R350 4Matic, 2007-2008 SLK280, SLK350, and SLK55 AMG, 2011-2014 SLS AMG Coupe, 2012 SLS AMG Cabriolet, 2013-2014 SLS AMG GT and SLS AMG GT Cabriolet, 2005 C230 Kompressor and C320, 2006-2007 C230, 2006-2011 C350, 2008-2011 C300 and C300 4Matic, 2010-2012 GLK350 and GLK350 4Matic and 2007-2008 Chrysler Crossfire vehicles. Upon deployment of the driver's frontal air bag, excessive internal pressure may cause the inflator to rupture.

Consequence

In the event of a crash necessitating deployment of the driver's frontal air bag, the inflator could rupture with metal fragments striking the driver or other occupants resulting in serious injury or death.

Remedy

MBUSA will their notify owners, and Fiat Chrysler will notify the affected Chrysler owners. Dealers for the respective brands will replace the driver's frontal air bag module, free of charge. This recall began November 2016. Mercedes-Benz owners may contact MBUSA customer service at 1-800-367-6372 and Chrysler owners may contact Fiat Chrysler customer service at 1-800-853-1403.

Open NHTSA investigations

EA21002

Desiccated Air Bag Inflator Rupture

From 2000 through 2017, Takata produced millions of air bag inflators using two types of phase-stabilized ammonium nitrate ("PSAN") propellant -- propellant 2004 and propellant 2004L. After prolonged exposure to high temperature cycles and humidity, inflators using propellant 2004 can degrade, causing the propellant to burn too quickly when ignited. The rapid burning can cause the inflator to rupture during deployment, potentially causing serious or even fatal injury to vehicle occupants. See 2016 Blomquist Report at www.nhtsa.gov/sites/nhtsa.gov/files/documents/expert_report-hrblomquist.pdf.Consequently, all frontal inflators using propellant 2004 that do not contain a "desiccant" (a substance that traps and holds moisture) in US vehicles are under recall. These "non-desiccated" inflators either have been or are required to be replaced.In some cases, the remedy part for these recalled inflators was, or will be, an inflator using either propellant 2004 or 2004L that does contain a desiccant. None of these "desiccated" remedy parts (which were installed in older model year vehicles) are currently under recall for a degradation concern. Certain subsets of desiccated PSAN inflators using propellant 2004 for use as original equipment, however, have been recalled for a degradation concern. All Takata inflators produced with propellant 2004L contain desiccant, and none of these desiccated inflators using propellant 2004L are under recall for a degradation concern. There have been no reported field ruptures in any non-recalled desiccated PSAN inflators.It is understood that desiccants fully saturate at some threshold, at which point any additional moisture will not be captured. This means the degradation process observed in non-desiccated inflators using propellant 2004 may also occur in non-recalled desiccated inflators using propellant 2004, assuming additional moisture enters the inflator and high temperature cycling occurs. Based on available information, desiccant saturation can occur within the first five years in the worst environments, and the time required for full saturation is affected by multiple factors. While no present safety risk has been identified, further work is needed to evaluate the future risk of non-recalled desiccated inflators using propellant 2004.Three entities -- Takata (now known as TK Global), the Independent Testing Coalition, and Exponent -- have been studying the long-term behavior of Takata desiccated PSAN inflators using propellant 2004L (as well as 2004) in the presence of moisture and temperature cycling. The research efforts, which include development of predictive modeling techniques and field sample analysis, are ongoing. To date, none of the researchers have identified field evidence showing that propellant 2004L is undergoing a degradation process that leads to aggressive deployment and potential rupture. However, the time in service of such inflators remains short compared to that of the inflators using propellant 2004. Further study is needed to assess the long-term safety of desiccated inflators using propellant 2004L.The Office of Defects Investigation is opening this investigation to examine whether a safety defect related to propellant degradation exists in non-recalled desiccated PSAN frontal inflators manufactured by Takata. This investigation will require extensive information on Takata production processes and surveys of inflators in the field. Lists of recall actions that may have used desiccated PSAN inflators as remedy parts, as well as the makes and models originally manufactured with them, is available with the downloadable version of this document (see nhtsa.gov/recalls?nhtsaId=EA21002 -- note this information is subject to change/revision as the investigation proceeds). This investigation does not supersede EA15-001, which remains open.

Consumer complaints filed with NHTSA

Representative excerpts, cleaned of personal information. These are consumer statements, not verified defects.

“I was involved in a head on collision when a motorist driving in the wrong lane hit the front of my car in the evening of 10/2/24. The impact was huge and my car was totaled. However, my airbag did not deploy and I hit my chest and knees very hard against the steering wheel and dashboard. Airbag…”

Complaint filed with NHTSA · Airbags · October 2, 2024 · crash

“I WAS DRIVING ON THE TURNPIKE AND THANK GOD NO OTHER CARS WERE NEXT TO ME. SOMETIMES WHEN I GO OVER 50 THE CAR TENDS TO PULL IN ANOTHER DIRECTION. I TOOK IT TO GET SERVICE A WEEK AFTER I BOUGHT IT AND GOT MY CAR BACK 6MONTHS LATER. THAN THE ACCIDENT HAPPENED. THEY JUST REPLACED COMPUTER CHIP THEY…”

Complaint filed with NHTSA · Electrical System · August 12, 2011 · crash

“THE VEHICLE EMIT A FUEL ODOR FROM THE REAR. THIS IS DUE TO FUEL LEAKS COMING FROM THE GAS TANK ASSEMBLY. MERCEDES BENZ HAD THESE ISSUE FROM 2003 TO 2009 E CLASS. MY CAR MAKE IS 2010- E350 HAVING THE ABOVE PROBLEM BESIDES TAKATA AIR BAG. WHAT ARE MY OPTIONS? THE DEALER DOESN'T CARE OF THE ISSUE.…”

Complaint filed with NHTSA · Fuel System · January 15, 2018

“WE LEASED MERCEDES E350 YEAR 2010 IN FEBRUARY. CAR'S RESPONSE WAS VERY GOOD AND WE LIKED THE CAR VERY MUCH. ON JUNE 16 I DROVE THE CAR ON FREEWAY FOR ABOUT 23 MILES THEN ON THE ROAD FOR ANOTHER MILE WITH COUPLE OF RED LIGHT STOPS. THEN I TURNED LEFT INTO THE PARKING LOT AND RIGHT TURN IN TO THE…”

Complaint filed with NHTSA · Other · June 16, 2010 · crash

“ANOTHER CAR MADE AN ILLEGAL U-TURN AND CAUSED ME TO T-BONE ON HIS PASSENGER SIDE. FRONT OF MY CAR HIT HIS PASSENGER SIDE AND DRAGGED HIS CAR FOR ABOUT 10 FEET. AIR BAGS ON MY CAR DID NOT DEPLOY, SAFETY SYSTEM M-BRACE IN CAR FAILED AND DID NOT CALL SOS EITHER. CAR SAFETY SYSTEM DID NOT DETECT THE…”

Complaint filed with NHTSA · Suspension · August 7, 2014 · crash

2010 Mercedes-Benz E350 — common questions

Is the 2010 Mercedes-Benz E350 reliable?

NHTSA data argues against it: 229 complaints put the 2010 model at #6 of 15 E350 years, and a defect investigation remains open. It is one of the E350 years to avoid.

What are the most common 2010 E350 problems?

According to NHTSA complaint data, the leading problem areas are airbags (68 complaints), electrical system (21 complaints), other (20 complaints).

Does the 2010 Mercedes-Benz E350 have recalls?

Yes — NHTSA lists 4 recall campaigns affecting the 2010 Mercedes-Benz E350. Recall repairs are free at franchised dealers; check the VIN at nhtsa.gov/recalls to confirm the work was done.

Is the 2010 Mercedes-Benz E350 under NHTSA investigation?

Yes — an investigation remains open (Desiccated Air Bag Inflator Rupture). An open ODI action means NHTSA is actively assessing a possible defect.

Which Mercedes-Benz E350 years should you avoid?

Based on complaint rates and open investigations, the E350 years to avoid are 2006, 2007, 2014, 2011, 2012, 2010, 2013, 2016, 2015, 2017. The cleanest record among E350 years belongs to 2003.

Related

Based on NHTSA ODI data through June 2026. Complaints are consumer-reported and unverified. Updated July 5, 2026.

Compiled by Sharon Ben-Moshe, Founder.